September 09, 2024 6 min read

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    September marks new beginnings, a change of season, pumpkin spice lattes, and long-awaited crisp air. It also raises the question of polycystic ovary syndrome (PCOS) diagnosis—a topic many women struggle with year-round. The National Polycystic Ovary Syndrome Association recognizes September as PCOS Awareness Month, highlighting the importance of understanding this complex condition.

    One of the leading causes of female infertility, PCOS affects approximately six million women in the U.S. alone[1]. Since the root causes of PCOS t are not yet specified, diagnosing it can be a challenge. In this guide, we will discuss the common PCOS symptoms, management options, and the importance of PCOS awareness.

    Understanding PCOS

    PCOS affects women in their reproductive years and is characterized by multiple cysts forming on the outer ovary wall.These cysts are filled with fluid that contains immature eggs, also known as follicles. The follicles cannot release the eggs, compromising ovulation. While the mechanisms of this condition are well-researched, the root cause of PCOS still hasn’t been determined.[2]

    This disorder affects up to 15% of the female population worldwide. In addition to cysts forming, PCOS manifests in a few more abnormalities[3]:

    • Increased production of androgens (“male” sex hormones)
    • Affected secretion of gonadotropin (hormones affecting the activity of reproductive glands)
    • Chronic anovulation (lack of ovulatory phase)
    Painful and life-altering symptoms of PCOS

    While the exact cause of PCOS hasn’t been pinpointed, scientists have recognized significant risk factors. One is the genetic component, an important contributor to many medical disorders. Genomic studies have found that certain susceptibility genes, in combination with environmental factors, can largely contribute to the development of PCOS.[3]

    Therefore, the known causes and contributors to PCOS development include[3]:

    • Genetic susceptibility, making PCOS a highly heritable condition
    • Environmental factors, including toxins and endocrine-disrupting chemicals parabens, bisphenols, and triclosan[4]
    • Hormonal factors, including increased production of androgens and secretion of gonadotropin
    • Insulin resistance
    • Gut microbiota, as poor microbiome diversity can lead to insulin resistance, metabolic syndrome, and chronic inflammation
    • Physical activity (or lack thereof)
    • Obesity
    • Diabetes

    PCOS Symptoms to Look Out For

    Not every case of irregular periods is synonymous with PCOS, and not every PCOS case will manifest through increased period intensity and frequency. It is, however, very common for polycystic ovaries to disrupt the menstrual cycle, making it extremely unpleasant, unpredictable, or even absent.[5]

    PCOS has also been associated with changes in skin health, often triggering skin tags, hyperpigmentation, acne, and increasing sebum production. In turn, many women diagnosed with this condition struggle with an oily, problematic complexion. Due to increased androgen production associated with polycystic ovaries, even women who have never experienced skin issues may develop acne.

    If you’ve noticed excessive body hair growth, it may also result from excess male hormones. Hirsutism, or excess hair growth, is one of the main manifestations of polycystic ovary syndrome and can begin as early as puberty.[5

    To make matters worse, the boosted hair growth mainly affects the face and body, while women suffering from PCOS may experience thinning scalp hair and even pattern baldness. Androgenic alopecia, caused by excess testosterone levels, is a common hair-related issue associated with this condition.[6]

    Weight gain and its role in PCOS can be examined from both sides of the spectrum, as it can be the cause just as much as the symptom. In the majority of cases, women who have PCOS deal with increased insulin production or insulin dysfunction. This kind of scenario increases the chances of weight gain, while obesity also promotes the likelihood of polycystic ovaries.[7]

    Polycystic ovary syndrome has also been associated with poor mental health, especially if the patient has a negative body image due to the mentioned changes. Depression, anxiety, and confusion women deal with in this stage may seriously affect their sleep rhythm, self-esteem, social relationships, and quality of life.[8]

    Finally, PCOS is related to numerous other health issues, including cardiovascular problems, high cholesterol, hypertension, infertility, and type 2 diabetes.

    Diagnosing PCOS

    Clear signs of PCOS

    Your OBGYN will confirm that the symptoms you’ve been experiencing indeed point to PCOS if at least two of these statements are true[8]:

    1. Clear signs of increased androgen levels, manifested through hair loss and thinning, excess bodily and facial hair, acne, and high testosterone
    2. Polycystic ovaries—fluid-filled sacs—have been detected via ultrasound scan
    3. The menstrual cycle is disrupted, and periods are irregular or absent

    In addition to the ultrasound scan, your doctor will request a blood test to analyze hormone levels. While hormonal fluctuations aren’t identical in every PCOS case, the most common instances include raised levels of testosterone, estrogen, luteinizing hormone, anti-mullerian hormone, and insulin.[8]

    So, what makes PCOS diagnosis so complex?While the ultrasound may seem like the most reliable method, some cases of polycystic ovaries may not even show fluid-filled sacs on the scan. What’s more, symptoms commonly associated with this disorder, including heavy menstrual bleeding, might also be caused by issues such as polyps, uterine fibroids, and pelvic inflammatory disease.[8]

    In addition, irregularities in ovulation patterns and menstrual periods attributed to PCOS can be a consequence of puberty, menopause, use of certain medications, or even stress. This is precisely why so many women are misdiagnosed, or their symptoms aren’t taken seriously.[8]

    The Importance of PCOS Awareness

    Mood swings, painful periods, and hormonal fluctuations women deal with every month are often brushed off and minimized. We are constantly reminded that struggling with female health comes as a “part of the package,” and we just have to endure it. 

    In reality, heavy and crippling periods, an influx of negative thoughts, and compromised body image should not be taken lightly. PCOS is a multilayered, deeply rooted problem that impacts both physical and mental health. While it still may not be completely understood, it is no longer a complete mystery, and women need to join the conversation about their reproductive well-being.

    During September, PCOS Challenge: The National Polycystic Ovary Syndrome Association organizes events, offering resources and crucial information for the affected women. PCOS Awareness Month aims to break the stigma surrounding women’s health and provide scientifically-backed information that can improve patients’ lives. Find out more about upcoming events on their website

    Managing PCOS: Natural Solutions

    Living with PCOS doesn’t have to be life-altering. However, you may have to alter your lifestyle to truly notice positive changes and hopefully reverse this condition in the future. 

    Promising methods include:

    • Weight regulation: Even a small weight reduction of about 5% can improve your PCOS symptoms. It is essential to base your diet on real foods, excluding as many processed items as possible. There are also indications that a low-carb diet may be beneficial in PCOS management[9]
    • Regular exercise: A 2024 study on the impact of exercise on PCOS found that physical activity can improve ovarian function. This improvement is attributed to decreased body fat, promoted lean muscle mass, healthy weight, and hormonal balance that results from regular exercise[10]
    • Vitamin D supplementation: The “sunshine” vitamin is not only essential for mood regulation, but it also plays a vital role in glucose metabolism. Optimizing vitamin D levels can decrease insulin resistance and inhibit inflammation[11]
    • Curcumin supplementation: Speaking of inflammation, curcumin is one of the most effective natural anti-inflammatory agents. It is also known to reduce insulin resistance and promote ovulation[11]
    • Probiotics: Research has shown that women affected by PCOS lack gut microbiome diversity and have higher intestinal permeability. This means that toxins can pass through the intestine walls and cause inflammation, hence the need for probiotics to improve the gut flora and inhibit inflammation[12]
    • Acupuncture treatments: Many studies highlight the positive effects of acupuncture, including decreased body fat, appetite suppression, and improved ovarian blood flow[12]

    In Conclusion

    Polycystic ovary syndrome isn’t a topic that should be pushed under the rug. Its complexity should only be motivation to speak on it louder than ever—and this is precisely the aim of PCOS Awareness Month. If you’ve checked off most of the mentioned symptoms but haven’t been diagnosed yet, don’t hesitate to schedule a doctor’s appointment and do the necessary tests.

    If, on the other hand, you’ve already been diagnosed with PCOS, remember that small lifestyle changes can sometimes make the biggest difference. In addition to your doctor’s recommendations, listening to your body and prioritizing both mental and physical well-being is essential.

    Article References:

    1. Polycystic Ovary Syndrome.” Www.endocrine.org, www.endocrine.org/patient-engagement/endocrine-library/pcos#:~:text=PCOS%20affects%207%E2%80%9310%25%20of.
    2. Mayo Clinic. “Polycystic Ovary Syndrome (PCOS) - Symptoms and Causes.” Mayo Clinic, 8 Sept. 2022, www.mayoclinic.org/diseases-conditions/pcos/symptoms-causes/syc-20353439.
    3. Dapas, Matthew, and Andrea Dunaif. “Deconstructing a Syndrome: Genomic Insights Into PCOS Causal Mechanisms and Classification.” Endocrine reviews vol. 43,6 (2022): 927-965. doi:10.1210/endrev/bnac001
    4. Srnovršnik, Tinkara et al. “Polycystic Ovary Syndrome and Endocrine Disruptors(Bisphenols, Parabens, and Triclosan)-A Systematic Review.” Life (Basel, Switzerland) vol. 13,1 138. 4 Jan. 2023, doi:10.3390/life13010138
    5. World Health Organization. “Polycystic Ovary Syndrome.” World Health Organization, 28 June 2023, www.who.int/news-room/fact-sheets/detail/polycystic-ovary-syndrome.
    6. https://www.facebook.com/verywell. “Hair Loss and PCOS: What You Can Do.” Verywell Health, 2022, www.verywellhealth.com/androgenic-alopecia-2616683#:~:text=Androgenic%20alopecia%20is%20a%20patterned. Accessed 9 Sept. 2024.
    7. Polycystic Ovarian Syndrome (PCOS) and Obesity.” Obesity Action Coalition, www.obesityaction.org/resources/polycystic-ovarian-syndrome-pcos-and-obesity/#:~:text=Women%20with%20PCOS%20produce%20too.
    8. Polycystic Ovary Syndrome.” Www.who.int, 28 June 2023, www.who.int/news-room/fact-sheets/detail/polycystic-ovary-syndrome#:~:text=PCOS%20can%20also%20cause%20anxiety.
    9. NHS. “Treatment-Polycystic Ovary Syndrome.” NHS, 11 Oct. 2022, www.nhs.uk/conditions/polycystic-ovary-syndrome-pcos/treatment/.
    10. Sabag, Angelo, et al. “Exercise in the Management of Polycystic Ovary Syndrome: A Position Statement from Exercise and Sport Science Australia.” Journal of Science and Medicine in Sport, 1 May 2024, https://doi.org/10.1016/j.jsams.2024.05.015.
    11. Kiani, Aysha Karim et al. “Dietary supplements for polycystic ovary syndrome.” Journal of preventive medicine and hygiene vol. 63,2 Suppl 3 E206-E213. 17 Oct. 2022, doi:10.15167/2421-4248/jpmh2022.63.2S3.2762
    12. Alesi, Simon et al. “Nutritional Supplements and Complementary Therapies in Polycystic Ovary Syndrome.” Advances in nutrition (Bethesda, Md.) vol. 13,4 (2022): 1243-1266. doi:10.1093/advances/nmab141



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